3D Bioplotter Research Papers

Displaying all papers about Adipose Tissue Regeneration (1 results)

Effects of tunable, 3D-bioprinted hydrogels on human brown adipocyte behavior and metabolic function

Acta Biomaterialia 2018 Volume 71, Pages 486-495

Obesity and its related health complications cause billions of dollars in healthcare costs annually in the United States, and there are yet to be safe and long-lasting anti-obesity approaches. Using brown adipose tissue (BAT) is a promising approach, as it uses fats for energy expenditure. However, the effect of the microenvironment on human thermogenic brown adipogenesis and how to generate clinically relevant sized and functioning BAT are still unknown. In our current study, we evaluated the effects of endothelial growth medium exposure on brown adipogenesis of human brown adipose progenitors (BAP). We found that pre-exposing BAP to angiogenic factors promoted…