3D Bioplotter Research Papers

Displaying all papers by L. Tayebi (3 results)

Design of a new 3D‐printed joint plug

Asia‐Pacific Journal of Chemical Engineering 2019 Volume 14, Issue 6, Article e2360

This paper introduces a kit of parts as a novel three‐dimensional (3D)–printed joint plug, in which each of the parts function cooperatively to treat cartilage damage in joints of the human body (e.g., hips, wrists, elbow, knee, and ankle). Three required and one optional parts are involved in this plug. The first part is a 3D‐printed hard scaffold (bone portion) to accommodate bone cells, and the second is a 3D‐printed soft scaffold (cartilage portion) overlying the bone portion to accommodate chondrocytes. The third part of joint plug is a permeable membrane, termed film, to cover the entire plug to provide…

Development of 3D-printed PLGA/TiO2 nanocomposite scaffolds for bone tissue engineering applications

Materials Science and Engineering: C 2019 Volume 96, Pages 105-113

Porous scaffolds were 3D-printed using poly lactic-co-glycolic acid (PLGA)/TiO2 composite (10:1 weight ratio) for bone tissue engineering applications. Addition of TiO2 nanoparticles improved the compressive modulus of scaffolds. Differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA) revealed an increase in both glass transition temperature and thermal decomposition onset of the composite compared to pure PLGA. Furthermore, addition of TiO2 was found to enhance the wettability of the surface evidenced by reducing the contact angle from 90.5 ± 3.2 to 79.8 ± 2.4 which is in favor of cellular attachment and activity. The obtained results revealed that PLGA/TiO2 scaffolds significantly improved osteoblast proliferation compared to…

3D-printed thick structured gelatin membrane for engineering of heterogeneous tissues

Materials Letters 2018 Volume 217, Pages 39-43

Although biological membranes may look like a 2D assembly, they often have complex structures in their 3rd dimension. Using layer-by-layer assembly, 3D-printing can offer an advanced and unique approach for the fabrication of such models. However, printing of some widely used hydrogels, such as gelatin, encounters experimental difficulties due to their rheological properties. In this paper, we (a) discuss the complexities involved in printing gelatin, (b) offer a reproducible approach to overcome such difficulties, and (c) present the detailed design criteria and the production process of such 3D-printed gelatin membranes by exemplifying scaffolds suitable for growth of full-thickness oral mucosa…