3D Bioplotter Research Papers

Displaying all papers by I. T. M. Arkesteijn (1 results)

Corrugated round fibers to improve cell adhesion and proliferation in tissue engineering scaffolds

Acta Biomaterialia 2013 Volume 9, Issue 6, Pages 6928–6935

Optimal cell interaction with biomaterial scaffolds is one of the important requirements for the development of successful in vitro tissue-engineered tissues. Fast, efficient and spatially uniform cell adhesion can improve the clinical potential of engineered tissue. Three-dimensional (3-D) solid free form fabrication is one widely used scaffold fabrication technique today. By means of deposition of polymer fibers, scaffolds with various porosity, 3-D architecture and mechanical properties can be prepared. These scaffolds consist mostly of solid round fibers. In this study, it was hypothesized that a corrugated fiber morphology enhances cell adhesion and proliferation and therefore leads to the development of…