3D Bioplotter Research Papers

Displaying all papers by H. Zhang (3 results)

3D Bioprinting of the Sustained Drug Release Wound Dressing with Double-Crosslinked Hyaluronic-Acid-Based Hydrogels

Polymers 2019 Volume 11, Issue 10, Article 1584

Hyaluronic acid (HA)-based hydrogels are widely used in biomedical applications due to their excellent biocompatibility. HA can be Ultraviolet (UV)-crosslinked by modification with methacrylic anhydride (HA-MA) and crosslinked by modification with 3,3′-dithiobis(propionylhydrazide) (DTP) (HA-SH) via click reaction. In the study presented in this paper, a 3D-bioprinted, double-crosslinked, hyaluronic-acid-based hydrogel for wound dressing was proposed. The hydrogel was produced by mixing HA-MA and HA-SH at different weight ratios. The rheological test showed that the storage modulus (G’) of the HA-SH/HA-MA hydrogel increased with the increase in the HA-MA content. The hydrogel had a high swelling ratio and a high controlled degradation…

Fabrication of Highly Stretchable Conductors Based on 3D Printed Porous Poly(dimethylsiloxane) and Conductive Carbon Nanotubes/Graphene Network

ACS Applied Materials & Interfaces 2016 Volume 8, Issue 3, Pages 2187–2192

The combination of carbon nanomaterial with three-dimensional (3D) porous polymer substrates has been demonstrated to be an effective approach to manufacture high-performance stretchable conductive materials (SCMs). However, it remains a challenge to fabricate 3D-structured SCMs with outstanding electrical conductivity capability under large strain in a facile way. In this work, the 3D printing technique was employed to prepare 3D porous poly(dimethylsiloxane) (O-PDMS) which was then integrated with carbon nanotubes and graphene conductive network and resulted in highly stretchable conductors (OPCG). Two types of OPCG were prepared, and it has been demonstrated that the OPCG with split-level structure exhibited both higher…

Material design and photo-regulated hydrolytic degradation behavior of tissue engineering scaffolds fabricated via 3D fiber deposition

Journal of Materials Chemistry B 2016 Volume 5, Pages 329-340

An ideal behavior of a tissue engineering scaffold is that it degrades and reshapes at a rate that matches the formation of new tissues. However, this ideal situation may not occur as the scaffold often undergoes too slow or too fast degradation. To test the promise of the active control of scaffold degradation, in this work, a photo/water dual-degradable porous scaffold was designed and fabricated using a 3D fiber deposition (3DF) system from a linear biopolymer (named PLANB) that combined the o-nitrobenzyl linkages and hydrolysable ester bone in the polymer chains. The chemical structure, molecular weight and polydispersity of PLANB…