3D Bioplotter Research Papers

Displaying all papers by H. Yao (1 results)

Regeneration of the articular surface of the rabbit synovial joint by cell homing: a proof of concept study

The Lancet 2010 Volume 376, Issue 9739, Pages 440-448

Background A common approach for tissue regeneration is cell delivery, for example by direct transplantation of stem or progenitor cells. An alternative, by recruitment of endogenous cells, needs experimental evidence. We tested the hypothesis that the articular surface of the synovial joint can regenerate with a biological cue spatially embedded in an anatomically correct bioscaffold. Methods In this proof of concept study, the surface morphology of a rabbit proximal humeral joint was captured with laser scanning and reconstructed by computer-aided design. We fabricated an anatomically correct bioscaffold using a composite of poly-ɛ-caprolactone and hydroxyapatite. The entire articular surface of unilateral…