3D Bioplotter Research Papers

Displaying all papers by D. Hamann (1 results)

3D Fiber-Deposited Electrospun Integrated Scaffolds Enhance Cartilage Tissue Formation

Advanced Functional Materials 2008 Volume 18, Issue 1, Pages 53-60

Despite the periodical and completely interconnected pore network that characterizes rapid prototyped scaffolds, cell seeding efficiency remains still a critical factor for optimal tissue regeneration. This can be mainly attributed to the current resolution limits in pore size. We present here novel three-dimensional (3D) scaffolds fabricated by combining 3D fiber deposition (3DF) and electrospinning (ESP). Scaffolds consisted of integrated 3DF periodical macrofiber and random ESP microfiber networks (3DFESP). The 3DF scaffold provides structural integrity and mechanical properties, while the ESP network works as a “sieving” and cell entrapment system and offers?at the same time?cues at the extracellular matrix (ECM) scale….